Endovac-Dairy is powered by superior science and smart solutions

Endovac simplifies protocols by offering broader protection in a single vaccine powered by our exclusive immunostimulant, Immune Plus.

features

Protection from E. coli, Salmonella, Pasteurella, and Mannheimia bacteria

Immunostimulant

Safe in all trimesters of pregnancy

Safe in lactating cows

important information

No milk withholding time

21-day slaughter withdrawal

Store at 2-8° Celsius or 35-46°
Fahrenheit

36-month shelf life

dosage

First dose: 2 mL, intramuscularly

Second dose: 2 mL, intramuscularly, 2 to 3 weeks following the priming dose

Contact your veterinarian or
manufacturer for more information
about revaccination frequency

bottle sizes

40 mL, 20 doses

100 mL, 50 doses

200 mL, 100 doses

endovac-dairy with immune plus

Not all mastitis vaccines are created equal.

Endovac-Dairy not only provides your herd unmatched E. coli mastitis protection, but provides protection from multiple gram-negative bacterial diseases. This industry leading vaccine provides cattle in every stage of production protection from E. coli, Salmonella, Pasteurella, and Mannheimia bacteria while increasing the animal’s production of antibodies, B and T lymphocytes, and neutrophils.

Two Technologies in One Bottle

Endovac Vaccine

  • Protects against E. coli and Salmonella
  • Minimizes milk drop
  • Ensures safety without active endotoxins

Immune Plus

  • Activates the immune system for a stronger response
  • Increases antibodies, lymphocytes and neutrophils
  • Simplifies administration with no mixing and a low 2 mL dose

Immune Plus the Unique Immunostimulant

Immune Plus raises the overall immune system of the animal. This is important both for response to vaccination as well as overall health at critical times. Two key components of the immune system, lymphocytes and antibodies, are both significantly increased with Immune Plus. Elevating the animal’s own immune response to ward off harmful pathogens, as well as enhancing the ability to respond to all your vaccinations, is key.

The Power of Endovac-Dairy

The way most vaccines are built, multiple antigens have to be added to the vaccine to get protection from multiple bugs. This cocktail method means that the animal has to respond to lots of different antigens individually. Cattle can only respond efficiently to so many antigens at a time and stacking these can sometimes be hard on cattle. Endovac vaccine is different for two reasons. First, the way our core technology is built, it is broad spectrum with only one antigen. Our unique antigen is the core of gram-negative bacteria. Second, the Endovac vaccine does not have harmful active endotoxins. Safe and effective, Endovac vaccine paired with Immune Plus is a real solution for dairymen and calf raisers.

How is Endovac-Dairy administered?

Two doses are necessary for optimum
immunization.

Inject 2 mL intramuscularly and repeat in 2 to 3 weeks following the first dose.

Contact your veterinarian or manufacturer for
more information about revaccination frequency.

How is Endovac-Dairy supplied?

Endovac-Dairy with Immune Plus can be purchased through your veterinarian or from any major animal health distributor.

Endovac-Dairy is powered by superior science and smart solutions

Endovac simplifies protocols by offering broader protection in a single vaccine powered by our exclusive immunostimulant, Immune Plus.

features

Protection from E. coli, Salmonella, Pasteurella, and Mannheimia bacteria

Immunostimulant

Safe in all trimesters of pregnancy

Safe in lactating cows

important information

No milk withholding time

21-day slaughter withdrawal

Store at 2-8° Celsius or 35-46°
Fahrenheit

36-month shelf life

dosage

First dose: 2 mL, intramuscularly

Second dose: 2 mL, intramuscularly, 2 to 3 weeks following the priming dose

Contact your veterinarian or
manufacturer for more information
about revaccination frequency

bottle sizes

40 mL, 20 doses

100 mL, 50 doses

200 mL, 100 doses

endovac-dairy with immune plus

Not all mastitis vaccines are created equal.

Endovac-Dairy not only provides your herd unmatched E. coli mastitis protection, but provides protection from multiple gram-negative bacterial diseases. This industry leading vaccine provides cattle in every stage of production protection from E. coli, Salmonella, Pasteurella, and Mannheimia bacteria while increasing the animal’s production of antibodies, B and T lymphocytes, and neutrophils.

Two Technologies in One Bottle

Endovac Vaccine

  • Protects against E. coli and Salmonella
  • Minimizes milk drop
  • Ensures safety without active endotoxins

Immune Plus

  • Activates the immune system for a stronger response
  • Increases antibodies, lymphocytes and neutrophils
  • Simplifies administration with no mixing and a low 2 mL dose

Immune Plus the Unique Immunostimulant

Immune Plus raises the overall immune system of the animal. This is important both for response to vaccination as well as overall health at critical times. Two key components of the immune system, lymphocytes and antibodies, are both significantly increased with Immune Plus. Elevating the animal’s own immune response to ward off harmful pathogens, as well as enhancing the ability to respond to all your vaccinations, is key.

The Power of Endovac-Dairy

The way most vaccines are built, multiple antigens have to be added to the vaccine to get protection from multiple bugs. This cocktail method means that the animal has to respond to lots of different antigens individually. Cattle can only respond efficiently to so many antigens at a time and stacking these can sometimes be hard on cattle. Endovac vaccine is different for two reasons. First, the way our core technology is built, it is broad spectrum with only one antigen. Our unique antigen is the core of gram-negative bacteria. Second, the Endovac vaccine does not have harmful active endotoxins. Safe and effective, Endovac vaccine paired with Immune Plus is a real solution for dairymen and calf raisers.

How is Endovac-Dairy administered?

Two doses are necessary for optimum
immunization.

Inject 2 mL intramuscularly and repeat in 2 to 3 weeks following the first dose.

Contact your veterinarian or manufacturer for
more information about revaccination frequency.

How is Endovac-Dairy supplied?

Endovac-Dairy with Immune Plus can be purchased through your veterinarian or from any major animal health distributor.

Locate your Endovac Animal Health representative

Copyright © 2026 Endovac Animal Health.