ENDOVAC-Equi® for active immunity

No vaccine can prevent an intestine from being blocked or twisted nor a mare’s placenta from being retained. Horses vaccinated with ENDOVAC-Equi®, however, develop anti-endotoxin antibodies which neutralize the deadly endotoxins released during such a crisis. This reduction of endotoxins keeps the patient alive and allows corrective treatment to be more successful, according to veterinarians who use ENDOVAC-Equi® routinely.

Questions & Answers

Why is ENDOVAC-Equi® not recommended to be used during the active training periods?

Stress due to active training is known to create some immune suppression in the horse. Vaccination during active training is not recommended because of the potential for reduced immune responses. Horses in training should be vaccinated during the “off season” or during a rest period and allowed to exercise freely following vaccination.

How safe is ENDOVAC-Equi®?

ENDOVAC-Equi® has been tested in thousands of horses and is safe for horses six months of age. Infield safety studies, ENDOVAC-Equi® was given in a variety of situations and resulted in no anaphylaxis, abscesses or large swellings. Most horses did exhibit some tenderness at the injection site for 24-48 hours. Practitioners participating in these field studies compared the severity of the transient tenderness to that associated with other vaccines.

Why should I consider using ENDOVAC-Equi®

It is well documented that endotoxin-mediated disease is the #1 cause of death in horses, with mortality exceeding 50%. In the neonate, Salmonella sp. and E. coli are common causes of endotoxemias secondary to failure of passive transfer. The mortality rate may exceed that of the adult. To make a comparison, the mortality associated with Streptococcus equi, rhinopneumonitis and influenza combined is estimated at only 2-3%.