Two primary injections with one annual booster

The use of ENDOVAC-Dairy® is the only core-antigen vaccine with a unique and effective immune stimulant. The patented ImmunePlus® in combination with the mutant Re-17 bacterin protects against E. coli Mastitis and other endotoxin-mediated diseases caused by E. coli, Salmonella, Pasteurella multocida, and Pasteurella (mannheimia) hemolytica.

Questions & Answers

What is ENDOVAC-Dairy®?

ENDOVAC-Dairy® is an Re-17 mutant Salmonella typhimurium bacterin-toxoid. This vaccine utilizes an antigen which is devoid of the outer O-side chains resulting in an exposed cell wall. Since the cell walls of gram negative bacteria are virtually analogous, this “core antigen” vaccine provides cross-protection from many gram-negative endotoxemic diseases.

How does ENDOVAC-Dairy® reduce incidence and severity of E. coli mastitis?

Independent research has clearly shown the association of endotoxins and the clinical signs of E. coli mastitis. Core-antigen vaccines focus on endotoxins by providing anti-LPS antibodies in response to active immunization. In the largest and most comprehensive efficacy study performed in 1292 dairy cattle, ENDOVAC-Dairy® significantly reduced both the incidence and severity of E. coli mastitis due to E. coli, “The first USDA licensed product with this approval”.

Can ENDOVAC-Dairy® be used in lactating dairy cattle?

It is recommended that ENDOVAC-Dairy® be used in the dry period to most effectively immunize cattle prior to the time of the highest incidence of E. coli mastitis during early lactation. However, the vaccine is safe in all trimesters.

How is ENDOVAC-Dairy® administered?

Inject 2ml into the musculature of healthy cattle. Repeat in 2 or 3 weeks. Administer a 2ml booster dose annually. Not recommended for administration to mastitic cows or to septicemic cattle.

How is ENDOVAC-Dairy® supplied?

Protecting herd health with ENDOVAC-Dairy® with IMMUNE Plus® begins with a call to your veterinarian.

The vaccine is available in 20 dose (40ml), 50 dose (100ml) bottles and 100 dose (200mL) bottles from veterinarians and most major distributors.

ENDOVAC-Dairy® with IMMUNE Plus® a 36 month shelf life when properly refrigerated.